The ADE endgame - "Bomb Dropped last night"

vaccine
ade

#1

ADE, Antibody Dependent Enhancement

If you ever share one thread on this forum, share this thread and keep sharing it!

Titers sets off the Alarm Bells

What is a Titer?

An antibody titer is a type of blood test that determines the presence and level (titer) of antibodies in the blood. This test is carried out to investigate if there is an immune reaction triggered by foreign invaders (antigens) in the body.

I believe Dr. Robert Malone actually took the Moderna shot, when he didn’t see any ADE last winter, but now things are different, very different.

This is the thing no one wanted to see but the warning have been there form the very very start.


Reposting videos that appear in later posts here for quick reference:


Coronavirus 2020
BLOOD - Taking Down Humanity - Self spreading Vaccines or Vaccine Shedding: A Bio-weapon by another name?
Bacik apologises
Coronavirus 2020
Coronavirus 2020
Coronavirus 2020
2yrs+ Permanent lockdown - NO EXIT
Coronavirus 2020
Coronavirus 2020
Now we get to see videos just like China 2020
#2

Some brief info on ADE ( Antibody-dependent Enhancement)

What is ADE?

ADE occurs when the antibodies generated during an immune response recognize and bind to a pathogen, but they are unable to prevent infection. Instead, these antibodies act as a “Trojan horse,” allowing the pathogen to get into cells and exacerbate the immune response.

Is ADE caused by vaccines?

On a few occasions ADE has resulted from vaccination:

  • Respiratory syncytial virus (RSV) — RSV is a virus that commonly causes pneumonia in children. A vaccine was made by growing RSV, purifying it, and inactivating it with the chemical formaldehyde. In clinical trials, children who were given the vaccine were more likely to develop or die from pneumonia after infection with RSV. As a result of this finding, the vaccine trials stopped, and the vaccine was never submitted for approval or released to the public.
  • Measles — An early version of measles vaccine was made by inactivating measles virus using formaldehyde. Children who were vaccinated and later became infected with measles in the community developed high fevers, unusual rash, and an atypical form of pneumonia. Upon seeing these results, the vaccine was withdrawn from use, and those who received this version of the vaccine were recommended to be vaccinated again using the live, weakened measles vaccine, which does not cause ADE and is still in use today.

Src: https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-safety/antibody-dependent-enhancement-and-vaccines


#3

This is what people warned of since last year. This has been a known potential. Some assumed it was going to happen.

This sounds like ADE in a shot.

They have neutralised your antibodies. Horses mouth. Your immune system is now out sourced to Pharma forever.

Video: https://mobile.twitter.com/KernowMaiden/status/1408403156988579843

Is anyone else done with the use of the term “gold standard” in all of this.


#4

Apparently Robert Malone will be on Bannon’s war room today (sometime between 3-5pm Irish) to talk for an hour on this. They archive the shows, so could just watch afterwards.


#5

The plan to enslave humanity is based on ADE working as planned.

The Target is the immune system. The Vector of attack are the injectiona under a grand pretext, “Attack of the virus”, a cybernetic trojan to justify the injections program globally all at once - you might have comes across the vaccines are the virus meme, in your travels. Same thing.

  1. Problem: The immune system becomes 80% compromised by the "vaccine"
  2. Reaction: People start dying bad incl vaccinated -Ultra-Delta+ HARDER LOCKDOWN MADATORY
  3. Solution: Shots for all + Boosters for life, humans fully dependant on Big-Pharma to survive, cradle to grave.

They’re trying to swap out humanities immune system for an artificial and out-sourced solution. What could go wrong! Immunity as a service, for life.

This is TRANSHUMAN agenda in a nutshell.

An insurrection against GOD.

I BORG or…


Vaccinated vs. Non Vaccinated & the Vaccine Bonus
4th Quarter Lockdown 2021 - YELLOW ALERT
#6

PREDICTIVE PROGRAMMING!


#7

This was a great slot with Robert Malone - has anyone’s got the video link post it up!


#8

DR. ROBERT MALONE - DEEP DIVE INTO COVID


Coronavirus 2020
#9

STOP THE SHOT! - DR. ROGER HODKINSON - Must see!


#11

I found this article form last year that was already ringing alarm bells for this.

https://www.nature.com/articles/s41564-020-00789-5

Abstract
Antibody-based drugs and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being expedited through preclinical and clinical development. Data from the study of SARS-CoV and other respiratory viruses suggest that anti-SARS-CoV-2 antibodies could exacerbate COVID-19 through antibody-dependent enhancement (ADE). Previous respiratory syncytial virus and dengue virus vaccine studies revealed human clinical safety risks related to ADE, resulting in failed vaccine trials. Here, we describe key ADE mechanisms and discuss mitigation strategies for SARS-CoV-2 vaccines and therapies in development. We also outline recently published data to evaluate the risks and opportunities for antibody-based protection against SARS-CoV-2.


#12

Anyone who knows anything about immunology and past CV vaccines know that this has always been the problem with them.


#13

Over the Target

Robert W Malone, MD

1h, 7 tweets, 1 min read

FYI, the “GHION journal” was in fact hit with a large and coordinated DNS attack soon after I posted the link below.

"This morning, our website was hit with a severe denial-of-service attack; according to our Webhosting provider GoDaddy, more than 2 million hits from bots based in China took Ghion Journal offline for more than three hours.

What we do know is that this was a sophisticated effort that could not have been conducted by lone wolves, this was the work of nefarious entities that have the financial means and the technical capacity to shutter websites and silence the free flow of communication"

"Below is the article that most likely precipitated the attack, which only gives credence to the information that is contained in it. https://ghionjournal.com/fauci-nih-knew-covid-19-vaccines-could-lead-antibody-dependent-enhancement/

“There are powerful forces who are hell-bent on censoring independent journalists and denying untold numbers of people the right to make an informed decision vis-à-vis the experimental “vaccines” that are being shoved down our throats.”

<<This attack appears to have immediately followed my posting a link to this article on this twitter feed - robert>>

My posting this seems to have triggered yet another DNS attack! Wow. Stimulus response. Could probably use this to ferret out how this is being triggered by sniffing packet traffic associated with this twitter account.

Link: https://ghionjournal.com/fauci-nih-knew-covid-19-vaccines-could-lead-antibody-dependent-enhancement/

Archived link: https://archive.is/Sz3gK


Irish FOI Data-Release Proves Hospitals Were Never Under Strain In 2020
#14

ADE-Thing

ADE is like the B-Thing, a known thing, a documented thing, a pre-plaid pre-planned thing… ADE demolishes the edifice of reality, justify the 4th and Final Lockdown. Has to be, hope it is not, but it must be, maybe. Prepare. Do Prepare and maybe it won’t pan out this way but if it does, but the virus, the virus variants, the Delta, a Delta plane got hijacked 1989, Sept 11th, planes can cause a lot of distraction in the media, those variants whizzing about in the media, you don’t notice the B-Thing so easily do you? The ADE-Thing.

Informed consent disclosure to vaccine trial subjects of risk of COVID‐19 vaccines worsening clinical disease

Go to:

1. THE RISK OF ADE IN COVID‐19 VACCINES IS NON‐THEORETICAL AND COMPELLING

Vaccine‐elicited enhancement of disease was previously observed in human subjects with vaccines for respiratory syncytial virus (RSV), dengue virus and measles. 1 Vaccine‐elicited enhancement of disease was also observed with the SARS and MERS viruses and with feline coronavirus, which are closely related to SARS‐CoV‐2, the causative pathogen of COVID‐19 disease. The immune mechanisms of this enhancement have invariably involved antibodies, from direct antibody‐dependent enhancement, to immune complex formation by antibodies, albeit accompanied by various coordinated cellular responses, such as Th2 T‐cell skewing. 2 , 3 , 4 , 5 , 6 , 7 Notably, both neutralising and non‐neutralising antibodies have been implicated. A recent study revealed IgG‐mediated acute lung injury in vivo in macaques infected with SARS that correlated with a vaccine‐elicited, neutralising antibody response. 8 Inflammation and tissue damage in the lung in this animal model recapitulated the inflammation and tissue damage in the lungs of SARS‐infected patients who succumbed to the disease. The time course was also similar, with the worst damage occurring in delayed fashion in synchrony with ramping up of the immune response. Remarkably, neutralising antibodies controlled the virus in the animal, but then would precipitate a severe, tissue‐damaging, inflammatory response in the lung. This is a similar profile to immune complex‐mediated disease seen with RSV vaccines in the past, wherein vaccinees succumbed to fatal enhanced RSV disease because of the formation of antibody‐virus immune complexes that precipitated harmful, inflammatory immune responses. It is also similar to the clinical course of COVID‐19 patients, in whom severe COVID‐19 disease is associated with the development of anti‐SARS‐CoV‐2 serum antibodies, 9 with titres correlating directly with the severity of disease. 10 Conversely, subjects who recover quickly may have low or no anti‐SARS‐CoV‐2 serum antibodies. 11

The elicitation of antibodies, specifically neutralising antibodies, is the goal of nearly every current SARS‐CoV‐2 vaccine candidate. The prior evidence that vaccine‐elicited, antibody‐dependent enhancement (ADE) of disease is likely to occur to some degree with COVID‐19 vaccines is vertically consistent from controlled SARS studies in primates to clinical observations in SARS and COVID‐19. Thus, a finite, non‐theoretical risk is evident in the medical literature that vaccine candidates composed of the SARS‐CoV‐2 viral spike and eliciting anti‐SARS‐CoV‐2 antibodies, be they neutralising or not, place vaccinees at higher risk for more severe COVID‐19 disease when they encounter circulating viruses. Indeed, studies in mice of prior SARS vaccines revealed this exact phenotype, with four human vaccine candidates eliciting neutralising antibodies and protecting against SARS challenge, but viral re‐challenge of thus vaccinated animals resulting in immunopathologic lung disease. 5 Independently, SARS/MERS vaccine candidates, commonly exhibited ADE associated with high inflammatory morbidity in preclinical models, obstructing their advancement to the clinic. 4 , 12 SARS ADE of both disease in non‐human primates and viral infection of cells in vitro was clearly mapped to specific antibody‐targeted SARS viral spike epitopes. 6This phenomenon was consistent across a variety of vaccine platforms, including DNA, vector primes and virus‐like particles (VLP), irrespective of inoculation method (oral, intramuscular, subcutaneous, etc). An unknown variable is how long this tissue damage lasts, possibly resulting in permanent morbidity (eg, diabetes from pancreatic damage 7 ).

Current data on COVID‐19 vaccines is limited, but does not so far reveal evidence of ADE of disease. Non‐human primate studies of Moderna’s mRNA‐1273 vaccine showed excellent protection, with no detectable immunopathology. 13 Phase 1 trials of several vaccines have not reported any immunopathology in subjects administered the candidate vaccines. However, these subjects were unlikely to have yet encountered circulating virus. 14 Nevertheless, all preclinical studies to date have been performed with the Wuhan or closely related strains of the virus, while a mutant D614G virus is now the most prevalent circulating form. Several observations suggest that this alternative form may be antigenically distinct from the Wuhan derived strain, not so much in composition, but in conformation of the viral spike and exposure of neutralisation epitopes. 15 , 16 , 17 , 18 Similarly, Phase 1 and 2 clinical trials of vaccine candidates have only been designed around immunogenicity as an efficacy end point and have not been designed to capture exposure of subjects to circulating virus after vaccination, which is when ADE/immunopathology is designed to occur. Thus, the absence of ADE evidence in COVID‐19 vaccine data so far does not absolve investigators from disclosing the risk of enhanced disease to vaccine trial participants, and it remains a realistic, non‐theoretical risk to the subjects.

Go to:

2. CHALLENGES TO INFORMED CONSENT FOR COVID‐19 VACCINE STUDIES

Informed consent procedures for vaccine trials commonly include disclosure of very minor risks such as injection site reactions, rare risks from past, unrelated vaccines/viruses, such as Guillain‐Barre syndrome for swine flu (interest in which is likely behind the interest in Astra Zeneca’s recent vaccine transverse myelitis event) and generic statements about the risk of idiosyncratic systemic adverse events and death. Specific risks to research participants derived from biological mechanism are rarely included, often because of ambiguity about their applicability. 19

Signed consent forms from the COVID‐19 vaccine trials are not publicly available because of privacy concerns. They also vary from clinical site to clinical site, and sample consent forms on which they are based are not required to be disclosed until after the trial is over, if at all. However, these consent forms are usually very similar in content to the “Risks to participants” section of the trial protocols, which have been released publicly by Pfizer, Moderna and Johnson & Johnson for their COVID‐19 vaccine trials ( 20 & Supplement). As these three vaccines are representative of the diversity of vaccines being tested, it is very likely that the consent form inferred from these protocols is similar or identical to those from any and all of the vaccine trials currently underway. All three protocols mention the risk of disease enhancement by the vaccine, but all three list this risk last or next to last in the list of risks, after risks from the Ad26‐Cov2 vector, adenovirus vectors in general, risks of vaccination in general, risks for pregnancy and birth control (which are said to be “unknown”), risks of blood draws and risks from collection of nasal swab samples (for the Johnson and Johnson vaccine), after allergy, fainting, local site injection reaction, general systemic adverse reactions and laboratory abnormalities for the Moderna vaccine and after local site injection reactions and general systemic adverse events for the Pfizer vaccine. In addition, both Moderna and Johnson and Johnson term the risk of vaccine‐elicited disease enhancement as “theoretical.” Finally, in citing the risk, Pfizer and Moderna note prior evidence of vaccine‐elicited disease enhancement with RSV and dengue, as well as feline coronavirus (Pfizer) and measles (Moderna), however, SARS and MERS are not mentioned. Johnson and Johnson discusses SARS and MERS, but make an unusual scientific argument that vaccine‐elicited disease enhancement is because of non‐neutralising antibodies and Th2‐skewed cellular responses and that Ad26 vaccination does not exhibit this profile.Blank consent forms for AstraZeneca and Johnson and Johnson are also available online at https://restoringtrials.org/2020/09/18/covid19trialprotocolandstudydocs/, and while the AstraZeneca form clearly discloses the specific risk of ADE, the disclosure is listed last among risks only in an attached information sheet. In all, the evidence from the Pfizer, Moderna and Johnson & Johnson protocols for their COVID‐19 vaccine trials and the sample consent forms, when contrasted with the evidence for antibody‐dependent enhancement of disease presented by this report and widely available to any skilled practitioner in the field, establishes that patient comprehension of the specific risk that receiving the COVID‐19 vaccine could convert a subject from someone who experiences mild disease to someone who experiences severe disease, lasting morbidity or even death is unlikely to be achieved by the informed consent procedures planned for these clinical trials.

Medical ethics standards required that, given the extent of evidence in the medical literature reviewed above, the risk of ADE should be clearly and emphatically distinguished in the informed consent from risks observed rarely as well as the more obvious risk of lack of efficacy, which is unrelated to the specific risk of ADE. Based on the published literature, it should have been obvious to any skilled medical practitioner in 2019 that there is a significant risk to vaccine research subjects that they may experience severe disease once vaccinated, while they might only have experienced a mild, self‐limited disease if not vaccinated. The consent should also clearly distinguish the specific risk of worsened COVID‐19 disease from generic statements about risk of death and generic risk of lack of efficacy of the vaccine.

Go to:

## 3. CONCLUSION

Given the strong evidence that ADE is a non‐theoretical and compelling risk for COVID‐19 vaccines and the “laundry list” nature of informed consents, disclosure of the specific risk of worsened COVID‐19 disease from vaccination calls for a specific, separate, informed consent form and demonstration of patient comprehension in order to meet medical ethics standards. The informed consent process for ongoing COVID‐19 vaccine trials does not appear to meet this standard. While the COVID‐19 global health emergency justifies accelerated vaccine trials of candidates with known liabilities, such an acceleration is not inconsistent with additional attention paid to heightened informed consent procedures specific to COVID‐19 vaccine risks.


#15


#16

Cradle to Grave Kool ADE

Why the rush to September to inject so badly all? To protect before this winter?

Why the rush to approve in the US before then, is it before ADE kicks in preventing magical-approval?

… or is it because ADE has been Weaponised in a SHOT.

Come winter, real social immunity is floored, overwhelms health service, Gov go into max panic, pull hardest lockdown yet ever (Nov oh we need to extend the emergency power to get through this unforeseen crisis), it will only requires a low single digit death and hospitalisation uptick across the island to create deep dark winter doo doo time.

Add into the mix the release of another bio-weapon, now it’s chances of causing havoc are maximised in a population primed fro ADE… is this the neutron bomb of bio-weapons, empty nations for the taking. Resources resources resrouces, all those empty gaffs ya know.

Why would you do this to your population?

This could cause social breakdown to devastating effect. It is worst case scenario, or is it?

The ferrets all died (5 min)

Apr 29, 2019

A prominent pediatrician and medical researcher in the Philippines has been indicted over the failed—and many say premature—introduction of Dengvaxia, a vaccine against dengue that was yanked from the Philippine market in 2017 because of safety issues. If convicted of accusations leveled at her by the national Department of Justice (DOJ), Rose Capeding, 63, former head of the dengue department of the Research Institute for Tropical Medicine (RITM) here, could face up to 48 years in prison.

In February, prosecutors concluded there is probable cause to indict Capeding and 19 others for “reckless imprudence resulting [in] homicide,” because they “facilitated, with undue haste,” Dengvaxia’s approval and its rollout among Philippine schoolchildren.

Capeding, through her family, declined to comment, but her son Juhani Capeding says his mother “couldn’t have imagined” that submitting research to top medical journals could have led to “this point.” Some of Capeding’s colleagues agree. “As a scientist, I really feel so disgusted, dismayed, [and] heartbroken about the whole situation,” says Lulu Bravo, executive director of the Philippine Foundation for Vaccination here.

RFK also mentions RSV, there are a lot of reports this year that RSV is “surging”.

Aug 03 - Wisconsin sees big jump in RSV cases, a child respiratory illness usually seen in winter
Aug 04 - Children’s respiratory virus comes roaring back alongside delta variant
Aug 04 - Hospitals seeing unusual increase in RSV cases among children

Need a VAX for that Stat!

Jul 30 - Surprise! Pfizer jumps the queue and leaps into RSV vax contention as COVID helps turbocharge work
Aug 03 - Moderna Receives FDA Fast Track Designation for Respiratory Syncytial Virus (RSV) Vaccine (mRNA-1345)
Aug 03 - FDA Grants Fast Track Status to mRNA Respiratory Syncytial Virus Vaccine Candidate
Aug 04 - Clinical Research Associates looking for participants in RSV vaccine study

Israel the Canary in the Goldmine (10 min)

https://www.bitchute.com/video/ahPBYmoqTWQC/

Stevens also mentions VAERS whistle blower indicates deaths are closer to 50,000 as per @jmc early estimates, but shenanigans with eh system are at play.

Compilation (1:40 min) on the subject of ADE. Pathogenic Priming (March, 4th - 2021)

Robert Malone explains what ADE will look like.

Robert Malone explains what it will look like if people start getting ADE from Covid Vaccines

More info:

Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

Antibody-based drugs and vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being expedited through preclinical and clinical development. Data from the study of SARS-CoV and other respiratory viruses suggest that anti-SARS-CoV-2 antibodies could exacerbate COVID-19 through antibody-dependent enhancement (ADE). Previous respiratory syncytial virus and dengue virus vaccine studies revealed human clinical safety risks related to ADE, resulting in failed vaccine trials. Here, we describe key ADE mechanisms and discuss mitigation strategies for SARS-CoV-2 vaccines and therapies in development. We also outline recently published data to evaluate the risks and opportunities for antibody-based protection against SARS-CoV-2.

https://www.nature.com/articles/s41564-020-00789-5


Enter The Rabbits Kingdom

This Is Why They Are Killing Off Doctors, Microbiologists And Infectious Disease Experts: 2017 Story Warned They Were Working On Bioweapons And ‘Viral Pandemics’

https://archive.is/5roWO


4th Quarter Lockdown 2021 - YELLOW ALERT
#17

A Contrary Point of View (March, 16, 2021)

Early in the pandemic, scientists engaged in a flurry of discussions about the best way to construct COVID-19 vaccines to ensure their efficacy and safety. Some of these discussions centered around antibody-dependent enhancement of immunity (ADE), a potentially deadly immune phenomenon seen with other viral infections and vaccines.

So far, there have been no reports of ADE with COVID-19 vaccines. But the concerns about ADE with COVID-19 vaccines have resurfaced with the emergency of virus variants. What exactly is ADE? What do we know from past experience with it? And why do experts say it’s a non-issue with COVID-19 vaccines?


#18

Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination ?

Published:August 09, 2021

Highlights

  • Infection-enhancing antibodies have been detected in symptomatic Covid-19

  • Antibody dependent enhancement (ADE) is a potential concern for vaccines

  • Enhancing antibodies recognize both the Wuhan strain and Delta variants

  • ADE of Delta variants is a potential risk for current vaccines

  • Vaccine formulations lacking ADE epitope are suggested

Src: https://www.journalofinfection.com/article/S0163-4453(21)00392-3/fulltext#relatedArticles


#19

I will value my blood in gold. One fluid ounce for one Troy ounce 24kt. Non negotiable.


#20

ADE was always known to be a real outcome of the injections.

That list again, derived from FDA doc of 2020:

-Guillain-Barré syndrome
-Acute disseminated encephalomyelitis
-Transverse myelitis
-Encephalitis /myelitis/encephalomyelitis/meningoencephalitis/meningitis/en​cephalopathy
-Convulsions/seizures
-Stroke
-Narcolepsy and cataplexy
-Anaphylaxis
-Acute myocardial infarction
-Myocarditis/pericarditis
-Autoimmune disease
-Deaths
-Preganacy and birth outcomes
-Other acute demyelinating diseases
-Non-anaphylactic allergic reactions
-Thrombocytopenia
-Disseminated intervascular coagulation
-Venous thromboembolism
-Arthritis and arthralgia/joint pain
-Kawasaki disease
-Multisymptom Inflammatory Syndrome in Children
-Vaccine enhanced disease

Latest from Robert Malone.

Robert W Malone, MD
@RWMaloneMD
9h

Assuming this is verified, “reports from Israel suggest INCREASED RISK OF SEVERE DISEASE amongst those vaccinated early” => ADE. Just saying.

Quote Tweet

Who? What? When? Where?

@Jimmy_Jeans Replying to @RWMaloneMD

Dr. Walensky let the Israel cat out of the bag: “reports from Israel suggest INCREASED RISK OF SEVERE DISEASE amongst those vaccinated early”. So wait… despite all the rhetoric about reduced severity/hospitalization, Israel data suggests otherwise??

215.7K views

Video @ Src: https://twitter.com/RWMaloneMD/status/1428325173317492738

Buried in the replies:

Image

Yellow - 96% (188) “vacc”

Then we have this parallel, if correct: "CARCRASH" - 97% HSE COVID Hospital Admissions have 1 or 2 shots


#21

Narrative Shift FTW